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- The Use of Molecular Oxygen for Liquid Phase Aerobic Oxidations in Continuous Flow.
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Xiao-Yu Sun. Organo-di-Metallic Compounds or Reagents. Zhenfeng Xi. Trace Analysis with Nanomaterials. The selection of examples summarized in this review is clear evidence that many aerobic oxidation transformations can be performed effectively and safely under continuous flow conditions. Even pure O 2 , as opposed to synthetic air, can be safely harnessed in particular instances to provide highly convincing synthetic and manufacturing benefits. Nevertheless, the utilization of continuous flow reactors still poses significant challenges in terms of cost and lack of available infrastructure and expertise available within the synthetic chemistry community.
We are convinced that, for environmental, economic, regulatory and synthetic reasons, continuous flow aerobic oxidations will be embraced by scientists and engineers within academic laboratories, and the pharmaceutical and fine chemical manufacturing industries, where further exciting developments can be anticipated in the coming years.
Open access funding provided by University of Graz. We are grateful to Dr. Doris Dallinger for carefully proofreading this chapter. The original version of this article was revised: The publisher regrets that due to a conversion problem there were mistakes in this article. Change history.
The publisher regrets that due to a conversion problem there were mistakes in this article. National Center for Biotechnology Information , U.
crapdumbmuscprom.tk Topics in Current Chemistry Cham. Top Curr Chem Cham. Published online Dec Christopher A. Hone 1, 2 and C. Oliver Kappe 1, 2. Oliver Kappe.